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This can lead to avoidance or extreme discomfort in these situations

The medical data presented here are mainly acquired from large-scale toxin exposures as those recorded in the acute poisoning outbreak in Kenya in 2004 with 125 deaths (Probst et al., 2007), in Tanzania during 2016 with 68 affected individuals, or in the former members of Yugoslavia (Klari et al., 2013)

Conversely, the anti-inflammatory cytokines TGF-1 and interleukin-10 (IL-10) have been shown to restore BSCB integrity following nerve damage [155]